Most heparin drips will be initiated with a bolus injection of 80 units/kilogram intravenously, followed by a continuous infusion rate of 18 units/kilogram/hour. ĭosing recommendations vary for each indication.

The American College of Chest Physicians (ACCP) recommends using heparin for many other thrombotic states: atrial fibrillation undergoing cardioversion, endocarditis, systemic emboli, or venous thrombosis. During hospitalization, heparin will be used to bridge to oral anticoagulation, warfarin for mechanical and bioprosthetic valves.

Heparin is widely used in the hospital for many different off-label indications, for example, patients who present with acute coronary syndromes (ACS) and who undergo percutaneous coronary intervention (PCI). Heparin can also be used to prevent excess coagulation during procedures such as cardiac surgery, extracorporeal circulation, or dialysis, including continuous renal replacement therapy (CRRT). Unfractionated heparin is an anticoagulant indicated for both the prevention and treatment of thrombotic events such as deep vein thrombosis (DVT) and pulmonary embolism (PE) as well as atrial fibrillation (AF).

Antidote for high inr